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A few single-particle reconstructions generated with SIMPLE

 

 

SIMPLE 2.0

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PRIME

Alignment of beta-galactosidase cryo-EM images (courtesy of R. Henderson) using a random asymmetric initial 3D model (blob).

 

 

   

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PRIME

Alignment of ribosome cryo-EM images (Frank, 2009) using an unrelated molecule, RNA polymerase II, as initial 3D model.

 

 

   

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SIMPLE 1.0

 

 

Transcription Factor II D with TBP

Structure. 2009 Nov 11;17(11):1442-52.

EM DATA BANK (EMDB) / 5134

 

   

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Transcription Factor II D lacking TBP

Structure. 2009 Nov 11;17(11):1442-52.

EM DATA BANK (EMDB) / 5135

 

   

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Magnesium Chelatase BchID complex

Structure. 2010 Mar 10;18(3):354-65.

EM DATA BANK (EMDB) / 1676

 

   

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GroEl Chaperonin

J Struct Biol. 2009 Jul;167(1):83-94.

EM DATA BANK (EMDB) / 1587

 

   

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